Ideas

November 27, 2018

Published by admin_auro at November 27, 2018

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Molecular therapy for aging-associated diseases and Lifespan extension: Prostaglandin D2 (PGD2), the principal cyclooxygenase (COX2) metabolite of arachidonic acid, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down-regulation of its target gene, 27/November/2018, 6.29 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]

November 25, 2018

Published by admin_auro at November 25, 2018

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Ideas
Stroke

AP-1(Activator protein-1)-inducing compounds may protect you against stroke: AP-1 attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 25/November/2018, 8.16 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]

November 25, 2018

Published by admin_auro at November 25, 2018

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Mechanistic insights into how XBP-1 enhances learning, memory and cognition: XBP-1 increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 25/November/2018, 8.01 am

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

November 25, 2018

Published by admin_auro at November 25, 2018

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Probiotic-based therapy for arthritic pain: Probiotic Bacillus licheniformis increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 25/November/2018, 7.54 am

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows […]