Ideas

May 22, 2017

Vitamin-based derived Life-extension therapy: ATRA (A form of Vitamin-A) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 22/May/2017, 11.52 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
May 22, 2017

Vitamin-based therapy for pulmonary arterial hypertension: Cholecalciferol (a form of Vitamin-D) inhibits the development of pulmonary arterial hypertension via down regulation of Notch3 and its target gene Hes-5, 22/May/2017, 9.53 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
May 22, 2017

Anti-telomerase cancer therapy: Metformin, the widely used drug in the treatment of TIIDM, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/May/2017, 9.23 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
May 22, 2017

Natural product-derived therapy for Metastatic cancers: Myrtenal, found in Cardamom, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 22/May/2017, 8.51 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]