Ideas

August 19, 2017

Molecular therapy for metastatic prostate cancer: A therapeutic mix encompassing Nimbolide and N-Acetyl Cysteine (NAC)   inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 18/August/2017, 10.46 pm

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
August 18, 2017

 Molecular therapy for inflammation and arthritis: Auranofin increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 18/August/2017, 11.58 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
August 18, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing β-Cryptoxanthin, Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D dissolved in Hydrogen-rich water activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 18/August/2017, 11.52 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 18, 2017

Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Geniposide, isolated from Gardenia, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 18/August/2017, 11.27 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]