Ideas

A salty way to say no to pain: Hypertonic saline-based Pain therapy: Hypertonic saline (10%) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 22/May/2018, 11.48 pm
A salty way to say no to pain: Hypertonic saline-based Pain therapy: Hypertonic saline (10%) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 22/May/2018, 11.48 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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A sweet way to say no to myocardial diseases: Sugar-based therapy for cardiac repair and myocardial infarction: Raffinose, a trisaccharide isolated from cotton seed flour, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 22/May/2018, 11.35 pm
A sweet way to say no to myocardial diseases: Sugar-based therapy for cardiac repair and myocardial infarction: Raffinose, a trisaccharide isolated from cotton seed flour, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 22/May/2018, 11.35 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

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A fibrous way to say no to Cardiomyopathy: β-glucan, found abundantly in oats and barley, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 22/May/2018, 11.03 pm
A fibrous way to say no to Cardiomyopathy: β-glucan, found abundantly in oats and barley, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 22/May/2018, 11.03 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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A salty way to say no to cardiac diseases-hard to believe though (!): Hypertonic saline-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Hypertonic saline (10%) decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 22/May/2018, 3.45 pm
A salty way to say no to cardiac diseases-hard to believe though (!): Hypertonic saline-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Hypertonic saline (10%) decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 22/May/2018, 3.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston,…

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as  p53, TA-p73 and TA-p63, TIMP3, and CCM3/KRIT1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/May/2017, 4.56 pm
Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as  p53, TA-p73 and TA-p63, TIMP3, and CCM3/KRIT1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/May/2017, 4.56 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different tissue origin; (2) p53…

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Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 20/May/2018, 4.43 pm
Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 20/May/2018, 4.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

  What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:   Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the expression of ATG5 (Autophagy-related…

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