Ideas

Combinatorial therapy for Deafness: A therapeutic mix encompassing Docosahexaenoic acid (DHA), Extra virgin olive oil (EVOO), Cholecalciferol, Ajoene and DIM (DHAEVOOCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss via up regulation of its target genes, 29/April/2018, 7.15 am
Combinatorial therapy for Deafness: A therapeutic mix encompassing Docosahexaenoic acid (DHA), Extra virgin olive oil (EVOO), Cholecalciferol, Ajoene and DIM (DHAEVOOCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss via up regulation of its target genes, 29/April/2018, 7.15 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Combinatorial therapy for Deafness: A therapeutic mix encompassing Docosahexaenoic acid (DHA), Extra virgin olive oil (EVOO), Cholecalciferol, Ajoene and DIM (DHAEVOOCAD)  increases…

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A glycolipid way to say no to Diabetes Mellitus: α-Galactosylceramide, a synthetic glycolipid, augments the expression of FGF19 and FGF1, attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 29/April/2018, 6.56 am
A glycolipid way to say no to Diabetes Mellitus: α-Galactosylceramide, a synthetic glycolipid, augments the expression of FGF19 and FGF1, attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 29/April/2018, 6.56 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained remission of…

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Blue light based therapy for Cardiomyopathy: Intense blue light decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 28/April/2018, 12.05 am
Blue light based therapy for Cardiomyopathy: Intense blue light decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 28/April/2018, 12.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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A longevity-promoting molecule comes to the rescue of blood sugar disease(autoimmune diabetes (TIDM)): Resveratrol, found in grapes, mulberry, ground nuts and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 27/April/2018, 11.52 pm
A longevity-promoting molecule comes to the rescue of blood sugar disease(autoimmune diabetes (TIDM)): Resveratrol, found in grapes, mulberry, ground nuts and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 27/April/2018, 11.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan…

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Molecular therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing Atorvastatin, Fumerate and Vitamin-E (ANFEVE) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 27/April/2018, 11.41 pm
Molecular therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing Atorvastatin, Fumerate and Vitamin-E (ANFEVE) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 27/April/2018, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory of Molecular Target and Clinical…

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Blue light-based therapy for TIIDM and obesity-associated metabolic deficits: Intense blue light therapy increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 27/April/2018, 11.32 pm
Blue light-based therapy for TIIDM and obesity-associated metabolic deficits: Intense blue light therapy increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 27/April/2018, 11.32 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite by…

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