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Ideas

February 10, 2018

Activation of the PD-1 pathway for Pain therapy: D-3-Hydroxybutyrate (D3HB) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 10/February/2017, 8.00 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
February 10, 2018

Carbon monoxide-based therapy for pulmonary arterial hypertension: COR-M2 (CO (Carbon monoxide) Releasing Molecules-2) inhibits the development of pulmonary arterial hypertension via up regulation of its target gene Notch3, 10/February/2018, 7.31 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
February 10, 2018

Molecular therapy for Stroke:  Omeprazole (brand name: Prilosec and Losec), a drug used in the treatment of stomach and duodenal ulcers, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 10/February/2018, 7.04 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
February 10, 2018

Molecular therapy for Metabolic diseases: Rolipram, a phosphodiesterase-4 inhibitor and an investigational drug for depression, autoimmune diseases, Alzheimer’s disease,cognitive enhancement,spinal cord injury, asthma and COPD, increases the expression of Caveolin-1, stabilizes insulin receptor, promotes insulin sensitivity, increases vasorelaxation, and decreases the risk of hyperglycemia and TIIDM via up regulation of its target gene.., 10/February/2018, 6.55 am

Introduction: What they say A study from the Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland shows that “MicroRNAs 103 and 107 regulate insulin sensitivity.” This study was published, in the June […]
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