Ideas

Alternative sweetener-based Lifespan extension therapy: Fructooligosaccharide, an alternative sweetener 30-50% as sweet as sugar,   increases life span via up-regulation of its target gene BubR1, 2/April/2017, 12.05 pm
Alternative sweetener-based Lifespan extension therapy: Fructooligosaccharide, an alternative sweetener 30-50% as sweet as sugar,   increases life span via up-regulation of its target gene BubR1, 2/April/2017, 12.05 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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A sweet way to say no to Diabetes Mellitus: D-Mannose, a C-2 epimer of glucose, augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 2/April/2018, 11.30 am
A sweet way to say no to Diabetes Mellitus: D-Mannose, a C-2 epimer of glucose, augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 2/April/2018, 11.30 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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Sugar-based learning/memory/cognitive-enhancement therapy:Raffinose, a trisaccharide composed of galactose, glucose, and fructose,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 31/March/2018, 11.30 pm
Sugar-based learning/memory/cognitive-enhancement therapy:Raffinose, a trisaccharide composed of galactose, glucose, and fructose,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 31/March/2018, 11.30 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center for the Biology of…

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A sweet way to protect your heart from Myocardial Infarction: Inulin, a polymer of fructose, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 31/March/2018, 11.20 pm
A sweet way to protect your heart from Myocardial Infarction: Inulin, a polymer of fructose, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 31/March/2018, 11.20 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

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Treating cardiac diseases with branched-chain amino acids:  Branched chain amino acid-based therapy for Cardiomyopathy: A therapeutic mix encompassing branched chain amino acids (10g) decrease the expression of Sox6, restore the balance between slow- and fast-twitch myofiber proteins and alleviate Cardiomyopathy via up regulation of its target gene, 31/March/2018, 11.08 pm
Treating cardiac diseases with branched-chain amino acids:  Branched chain amino acid-based therapy for Cardiomyopathy: A therapeutic mix encompassing branched chain amino acids (10g) decrease the expression of Sox6, restore the balance between slow- and fast-twitch myofiber proteins and alleviate Cardiomyopathy via up regulation of its target gene, 31/March/2018, 11.08 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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A sweet way to treat pain: Trisaccharide-based activation of the PD-1 pathway for Pain therapy: Raffinose, a trisaccharide composed of galactose, glucose, and fructose, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 31/March/2018, 10.57 pm
A sweet way to treat pain: Trisaccharide-based activation of the PD-1 pathway for Pain therapy: Raffinose, a trisaccharide composed of galactose, glucose, and fructose, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 31/March/2018, 10.57 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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