Ideas

October 5, 2018

Published by admin_auro at October 5, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Act1 (Adaptor for IL-17 receptors) increases the expression of tumor suppressors genes, such as BTG2, TIMP3, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 5/October/2018, 11.28 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

October 5, 2018

Published by admin_auro at October 5, 2018

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A probiotic way to treat TIIDM and obesity-associated metabolic deficits: Probiotic Lactobaccilus gasseri SBT2055 increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down-regulation of its target gene, 5/October/2018, 11.01 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]

October 5, 2018

Published by admin_auro at October 5, 2018

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A probiotic way to stay free of diabetes: Probiotic Lactobacillus gasseri-based therapy for body weight control, energy homeostasis and TIIDM: Probiotic Lactobacillus gasseri inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 5/September/2018, 10.46 pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]

October 5, 2018

Published by admin_auro at October 5, 2018

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Ideas
NAFLD

A probiotic way to lower cholesterol, and triglycerides levels: Probiotic Lactobacillus Gasseri SBT 2055 (LG2055) decreases the levels of HMGCR, triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 5/October/2018, 10.27 pm

The significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]