Ideas – Page 236

September 29, 2018

Published by admin_auro at September 29, 2018

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A probiotic way to boost memory, learning, and cognition: Probiotic Bifidobacterium breve increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down-regulation of its target genes, 29/September/2018, 11.33 pm

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

September 28, 2018

Published by admin_auro at September 28, 2018

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Consuming a Probiotic once a day may insulate your heart against cardiac dysfunction: Probiotic Bifidobacterium Breve-based adjunct therapy for cardiac hypertrophy and fibrosis: Probiotic Bifidobacterium Breve decreases Mir-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 28/September/2018, 3.09 pm

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]

September 28, 2018

Published by admin_auro at September 28, 2018

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Activating tumor suppressor gene network for cancer therapeutics: Pioglitazone (trade name: Actos), an anti-diabetic drug, increases the expression of tumor suppressors genes, such as LATS1, SMARCA4, p53, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 28/September/2018, 7.49 am

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

September 28, 2018

Published by admin_auro at September 28, 2018

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Turning on the cancer-protecting tumor suppressor network in mutant p53-expressing human tumors: Andrographolide, isolated from Andrographis paniculata, increases the expression of tumor suppressors genes, such as BTG2, CADM1, p53, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 28/September/2018, 7.14 am

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]