Ideas

Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am
Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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Antiviral therapy for HIV virus: Ribavirin/Tribavirin, an antiviral medication used in the treatment of RSV infection, hepatitis C, and viral hemorrhagic fever,  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 31/October/2017, 10.43am
Antiviral therapy for HIV virus: Ribavirin/Tribavirin, an antiviral medication used in the treatment of RSV infection, hepatitis C, and viral hemorrhagic fever,  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 31/October/2017, 10.43am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, New York, NY 10032,…

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Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing iallyl disulfide, Isoorientin and Resveratrol (DIR) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 31/September/2017, 10.35 am
Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing iallyl disulfide, Isoorientin and Resveratrol (DIR) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 31/September/2017, 10.35 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Regenerative therapy for muscle atrophy: Simvastatin (Brand name: Zocor), a lipid lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 31/October/2017, 10.25 am
Regenerative therapy for muscle atrophy: Simvastatin (Brand name: Zocor), a lipid lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 31/October/2017, 10.25 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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Natural product-based therapy for Inflammatory bowel disease(IBD): Carnosic acid, found in Rosmarinus officinalis and Common sage/Salvia officinalis, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 30/August/2017, 10.37 am
Natural product-based therapy for Inflammatory bowel disease(IBD): Carnosic acid, found in Rosmarinus officinalis and Common sage/Salvia officinalis, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 30/August/2017, 10.37 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK shows that “Oncostatin…

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Molecular therapy for Glaucoma: Netoglitazone, a blood glucose-lowering drug, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 30/October/2017, 9.29 am
Molecular therapy for Glaucoma: Netoglitazone, a blood glucose-lowering drug, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 30/October/2017, 9.29 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, USA; The Howard Hughes…

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