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Ideas

October 18, 2017

Lifespan extension therapy: Rivoglitazone, an anti-hyperglycemic drug,  may increase life span via up-regulation of its target gene BubR1, 19/October/2017, 1.21 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
October 18, 2017

Natural product therapy for pulmonary arterial hypertension: A therapeutic mix encompassing Curcumin and Quercetin, isolated from Turmeric and Elder berries, respectively, inhibits the development of pulmonary arterial hypertension via down regulation of  Notch3 and its target gene Hes-5, 19/October/2017, 1.00 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
October 18, 2017

Small molecule-based GPC2 pathway blockade enhances the efficacy of Cancer immunotherapy in Neuroblastoma: A therapeutic mix encompassing Ascorbate, Delta-tocotrienol, Dehydroleucodine, & Forodesine [ADDF] inhibits the expression of GPC2, increases IFNγ signalling, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, inhibits neuroblastoma proliferation, decreases tumor burden and increases survival via up-regulation of its target gene, 18/October/2017, 11.27 pm

Introduction:What they say: A recent study from Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA […]
October 17, 2017

Natural product-based therapy for Deafness: A therapeutic mix encompassing Salvianolic Acid B,  Cardamomin, Cholecalciferol  and DIM (SABCCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  and improves hearing loss via up regulation of its target genes, 18/October/2017, 12.10 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based therapy for Deafness: A therapeutic mix encompassing Salvianolic Acid B,  Cardamomin, Cholecalciferol  and […]
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