Ideas

April 2, 2018

Published by admin_auro at April 2, 2018

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Ideas

Treating pain with sweet: Sugar-based activation of the PD-1 pathway for Pain therapy: D-Mannose, a C-2 epimer of glucose commonly used in the treatment of urinary tract infections, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 2/April/2018, 12.31 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]

April 2, 2018

Published by admin_auro at April 2, 2018

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A sweet way to decrease blood pressure/sugar and extend lifespan: Sugar-based Lifespan extension therapy: D-Allose, a C-3 epimer of glucose, prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 4/April/2018, 12.19 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]

April 2, 2018

Published by admin_auro at April 2, 2018

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Alternative sweetener-based Lifespan extension therapy: Fructooligosaccharide, an alternative sweetener 30-50% as sweet as sugar, increases life span via up-regulation of its target gene BubR1, 2/April/2017, 12.05 pm

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]

April 2, 2018

Published by admin_auro at April 2, 2018

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A sweet way to say no to Diabetes Mellitus: D-Mannose, a C-2 epimer of glucose, augments the expression of FGF19 and FGF1, attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 2/April/2018, 11.30 am

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]