Ideas

March 3, 2018
Published by admin_auro at March 3, 2018
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Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Sirolimus, an immunosuppressant and longevity promoter, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 3/March/2018, 8.38 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Polyamine-based therapy for anxiety and depression:  Spermine, a natural polyamine, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 2/March/2018, 8.13 am

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Molecular therapy for tuberculosis: Triclosan, an antibacterial and antifungal agent found commonly in toothpastes, soaps, among others, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 2/March/2018, 8.06 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Polyamine-based Lifespan extension therapy:  Spermidine increases life span via up-regulation of its target gene BubR1, 2/March/2018, 7.55 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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