Ideas

March 17, 2018

Published by admin_auro at March 17, 2018

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A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allose, an aldohexose sugar and C-3 epimer of glucose, may increase life span via up-regulation of its target gene BubR1, 17/March/2018, 7.07 am

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]

March 17, 2018

Published by admin_auro at March 17, 2018

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Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Spermidine, a natural polyamine, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 17/March/2018, 6.50 am

Introduction: What they say: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]

March 16, 2018

Published by admin_auro at March 16, 2018

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Ideas
Pain

A sweet way to say no to pain: Sugar-based PD-1 pathway activation for Pain therapy: Phyllodulcin, a natural sweetener 400-800 times sweeter than sugar, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 16/March/2017, 7.40 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]

March 16, 2018

Published by admin_auro at March 16, 2018

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A sweet way to say no to Autoimmune diabetes (TIDM): Sugar-based therapy for autoimmune diabetes (TIDM): Trehalose, a natural sweetener isolated from mushrooms among others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 16/March/2018, 7.20 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]