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Ideas

September 26, 2017

Natural product-derived exercise mementics therapy for Metabolic disease: Ursolic acid, isolated from Rosemary, Thyme, Mirablis Jalaba, increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 26/September/2017, 5.51 am

Introduction: What they say A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows […]
September 24, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Cholecalciferol,Catalpol, Maresin, 3’3’ –Diindoly Methane (DIM) , Lutein, & Baicalin (CCMDLB)   activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5) , 25/September/2017, 12.31 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
September 24, 2017

Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
September 24, 2017

Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase […]
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