Ideas

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm
Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Natural product-derived therapy for anxiety and depression: Berberine, isolated from Berberis vulgaris, among others,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 24/September/2017, 12. 07 am
Natural product-derived therapy for anxiety and depression: Berberine, isolated from Berberis vulgaris, among others,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 24/September/2017, 12. 07 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Shikonin, Amitriptyline, Rosustatin,Cholecalciferol, Hypericin, Nimpolide, PEITC, Linalool and Salinomycin (SARCHNPLS) inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 23/September/2017, 11.51 pm
Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Shikonin, Amitriptyline, Rosustatin,Cholecalciferol, Hypericin, Nimpolide, PEITC, Linalool and Salinomycin (SARCHNPLS) inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 23/September/2017, 11.51 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands has identified CMTM6 and CMTM4 as…

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Natural product-derived therapy for inflammation and arthritis: Berberine, isolated from Berberis Vulgaris, increases IL-9 levels, increases proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 23/September/2017, 11.11 pm
Natural product-derived therapy for inflammation and arthritis: Berberine, isolated from Berberis Vulgaris, increases IL-9 levels, increases proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 23/September/2017, 11.11 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that “Resolution of inflammation by…

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Natural product-derived therapy for Stroke: Catalpol, isolated from Catalpa, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 23/June/2017, 11.01 pm
Natural product-derived therapy for Stroke: Catalpol, isolated from Catalpa, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 23/June/2017, 11.01 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Withaferin A (WA), Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 23/September/2017, 2.06 am
Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Withaferin A (WA), Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 23/September/2017, 2.06 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published, in the online…

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