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Ideas

September 26, 2017

Molecular therapy for muscle atrophy and wasting: Fluoxetine, an anti-depressant drug, increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 26/September/2017, 6.24 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
September 26, 2017

Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Berberine, isolated from Berberis vulgais, among others, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 26/September/2017, 6.05 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
September 26, 2017

Natural product-derived exercise mementics therapy for Metabolic disease: Ursolic acid, isolated from Rosemary, Thyme, Mirablis Jalaba, increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 26/September/2017, 5.51 am

Introduction: What they say A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows […]
September 24, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Cholecalciferol,Catalpol, Maresin, 3’3’ –Diindoly Methane (DIM) , Lutein, & Baicalin (CCMDLB)   activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5) , 25/September/2017, 12.31 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
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