Ideas

March 12, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Rumenic acid, a conjugated linoleic acid found in dairy products, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 12/March/2018, 10.57 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
March 12, 2018

Regenerative therapy for improving memory in aged individuals: Valine, a branched-chain amino acid, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 12/March/2018, 10.47 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
March 12, 2018

Amino acid-based therapy for glucose homeostasis and TIIDM: Tryptophan, an essential amino acid  and precursor of the neurotransmitter serotonin and the hormone melatonin,  increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 12/March/2018, 10.38 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
March 12, 2018

Amino acid-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:Isoleucine, a branched-chain amino acid, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 12/March/2018, 10.28 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
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