Ideas

March 8, 2018

Small-molecule based therapy for reversing autoimmune diabetes (TIDM): Lactoferrin, a globular glycoprotein commonly found in secretory fluids, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 8/March/2018, 7.06 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
March 8, 2018

Combination (Amino acid + Polyamine) therapy for reversing TIIDM: A pharmaceutical mixture encompassing  L-Arginine and Spermidine augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM, via up regulation of its target gene, 8/March/2018, 6.55 am

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
March 8, 2018

Amino acid-based therapy for body weight control, energy homeostasis and TIIDM: L-Arginine, a non-essential amino acid that aids in blood flow and in maintaining optimal nitric oxide levels, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 8/March/2018, 6.36 am

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]
March 8, 2018

Natural product-based therapy for inflammation and arthritis: Sulforaphane, found in Broccoli among others,  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 8/March/2018, 6.18 am

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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