Ideas

February 21, 2018
Published by admin_auro at February 21, 2018
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Amino acid-based therapy for autoimmune diabetes (TIDM): L-Arginine, a semi-essential amino acid, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 21/February/2018, 7.33 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
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February 21, 2018
Published by admin_auro at February 21, 2018
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Combinatorial therapy for Cancer: A therapeutic mix encompassing Gedunin,  Atorvastatin, Desipramine, Sulfasalazine (SSZ), SAHA(suberanilohydroxamic acid)/Vorinostat (GADSS)  increases the expression of REV-ERBa, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival, via up-regulation of its target gene, 21/February/2018, 6.55 am

Introduction:What they say: A recent study from Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA and Laboratory of Genetics, Salk Institute […]
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February 21, 2018
Published by admin_auro at February 21, 2018
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Natural product-based combinatorial therapy for PTEN-deficient cancer: A therapeutic mix encompassing macbecin, temozolomide, EGCG, salinomycin, fluvastatin and chloroquine (MTESFC) decreases the expression of CHD1, increases the expression of a number of tumor suppressor genes, inhibits pro-survival TNF-NF-kB gene network, and suppresses tumorigenesis of PTEN-deficient cancers, 21/February/2018, 6.29 am

Introduction: What they say: A study from the Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA shows that “Synthetic […]
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February 21, 2018
Published by admin_auro at February 21, 2018
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Combinatorial therapy for blood-stage Plasmodium infection: A therapeutic mix encompassing  Ketorolac (Trade name: Toradol, Acular, Sprix] and Aspirin (anti-inflammatory drugs) decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 21/February/2018, 6.13 am

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
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