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Ideas

September 14, 2017

Antiviral therapy for HIV virus: Efavirenz, an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 14/September/2017, 11.55 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Antiviral therapy for HIV virus: Efavirenz, an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, […]
September 13, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM:  A therapeutic mix [BAEG]  encompassing Betulinic acid (BA) and Eugenol (EG) decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 13/September/2017, 10.46 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
September 13, 2017

Natural product therapy for pulmonary arterial hypertension: Punicalagin (PG), isolated from Punica granatum,  inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 13/September/2017, 9.58 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
September 13, 2017

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Ursodeoxycholic acid (UDCA) [Trade name: Actigall, Udcasid] promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 12/September/2017, 9.49 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while only 6-25% of Asian populations suffer from it; […]
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