Ideas

October 23, 2017

Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing Linalool, Gastrodin, Puerarin (LGP) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 23/October/2017, 11.58 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
October 23, 2017

Lifespan extension therapy: Kaempferol, found abundantly in Apples and Aloe vera,  may increase life span via up-regulation of its target gene BubR1, 23/October/2017, 11.51 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
October 23, 2017

Natural product-based therapy for Deafness: A therapeutic mix encompassing Catalpol, Emodin, Cholecalciferol, and DIM  (CECAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 23/October/2017, 9.17 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Natural product-based therapy for Deafness: A therapeutic mix encompassing Catalpol, Emodin, Cholecalciferol, and DIM […]
October 21, 2017

Molecular therapy for pulmonary arterial hypertension: Digoxin, commonly used in the treatment of heart failure and arrhythmias, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 22/October/2017, 1.05 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.“ This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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