Ideas

February 19, 2018

Published by admin_auro at February 19, 2018

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Combinatorial therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Pantoprazole, Epicatechin and Matrine (PPEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 20/February/2018, 12.28 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]

February 19, 2018

Published by admin_auro at February 19, 2018

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Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture encompassing Pyridoxamine (PM) and Melatonin decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 20/February/2017, 12.08 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]

February 19, 2018

Published by admin_auro at February 19, 2018

Categories

Ideas
NAFLD

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Omeprazole promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 19/February/2017, 11.59 pm

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]

February 19, 2018

Published by admin_auro at February 19, 2018

Categories

Combinatorial therapy for Metastatic cancers: A pharmaceutical mixture encompassing Docosahexaenoic acid (DHA) and Aspirin (ASA) increases the expression of tumor/metastatic suppressors RECK1 and CADM1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 19/February/2018, 11.54 pm

From significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]