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Ideas

August 30, 2017

Lifespan extension therapy: Olmesartan, a drug used in the treatment of high blood pressure,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/August/2017, 11.52 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
August 30, 2017

Molecular-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Rivaroxaban (brand name: Xarelto), an anticoagulant drug, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 30/August/2017, 11.43 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
August 29, 2017

Natural product-derived  therapy for enhancing anti-cancer immunity: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemesia anuua L, decreases the level of LATS1/2 (large tumor suppressor 1 and 2), increases immunogenicity of tumors, enhances anti-tumor immune responses, and inhibits tumor growth via down regulation of its target gene, 30/August/2017, 1.26 am

Introduction: What they say:  A study from the Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA shows that […]
August 29, 2017

Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of tumor suppressors RECK1 and CADM1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 30/August/2017, 12.50 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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