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Ideas

August 21, 2017

Natural product therapy for pulmonary arterial hypertension: Artesunate, isolated from Artemesia Annua L,  inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 22/August/2017, 1.36 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the […]
August 21, 2017

Natural product-derived therapy for tuberculosis: N-Acetylcysteine (NAC) deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 22/August/2017, 1.28 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
August 21, 2017

Natural product-based therapy for anxiety and depression: Dihydromyricetin (DHM), a natural flavonoid derived from Ampeopsis Grossdentatam, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 22/August/2017, 12.54 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
August 21, 2017

Natural product-derived therapy for gynecologic cancers: A therapeutic mix encompassing N-Acetylcysteine, Capsaicin, and Sulforaphane (NCS) inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 21/August/2017, 11.58 am

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on […]
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