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Ideas

August 22, 2017

Natural product-derived therapy for prostate cancer: A therapeutic mix encompassing N-Acetylcysteine(NAC), Capsaicin, and Sulforaphane (NCS) inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 22/July/2017, 10.08 pm

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]
August 22, 2017

Antiviral therapy for Neuroinvasive West Nile virus: Ivermectin (Brand name:Heartguard/Mectizan) increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 22/August/2017, 9.55 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
August 21, 2017

Natural product therapy for pulmonary arterial hypertension: Artesunate, isolated from Artemesia Annua L,  inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 22/August/2017, 1.36 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the […]
August 21, 2017

Natural product-derived therapy for tuberculosis: N-Acetylcysteine (NAC) deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 22/August/2017, 1.28 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
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