Ideas

November 22, 2017

Molecular therapy for glioblastoma: A therapeutic mix encompassing Temozolomide (TMZ), 17-AAG, Simvastatin, Salinomycin, Linalool, Amitriptyline (TASSLA) inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 22/November/2017, 6.06 am

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
November 21, 2017

Natural product-derived combinatorial therapy for therapy-resistant cancers: A therapeutic mix encompassing encompassing   β-cryptoxanthin (BCX), Sodium butyrate, Fucoxanthin, Ganetespib, Rosuvastatin and Cyclophosphamide (BCXSFGRC) inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 21/November/2017, 10.49 pm

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, […]
November 21, 2017

Life-extension therapy: Licorine, isolated from Clivia Miniata, Lycoris  (surprise lilies), and Narcissus, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 21/November/2017, 7.43 am

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
November 20, 2017

Natural product therapy for pulmonary arterial hypertension: Enoxolone (also known as glycyrrhetinic acid) , one of the main components of Liquorice, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 21/November/2017, 12.41 am

What they say:   A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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