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Ideas

August 20, 2017

Molecular therapy for Metastatic cancers: Myrtenal, isolated  from Taxus, increases the expression of metastasis suppressors TAp63 and TPM1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 21/August/2017, 12.20 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
August 20, 2017

Natural product-derived therapy for therapy-resistant cancers: A therapeutic mix encompassing N-AcetylCysteine (NAC), Capsaicin and Sulforaphane inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 21/August/2017, 12.10 am

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, […]
August 20, 2017

Natural product therapy for pulmonary arterial hypertension: N-Acetylcysteine (NAC) inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 20/August/2017, 11.58 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the […]
August 19, 2017

Natural product-based therapy for Cardiomyopathy: Geniposide, isolated from Gardenia and among others, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 20/August/2017,  1.15 am

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
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