Ideas

Natural product-derived therapy for Myocardial Infarction: Artesunate, a derivative of artemisinin isolated from Artemesia annua L,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via  up-regulation of PNUTS, 24/July/2017, 12.10 am

Natural product-derived therapy for Myocardial Infarction: Artesunate, a derivative of artemisinin isolated from Artemesia annua L,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via  up-regulation of PNUTS, 24/July/2017, 12.10 am 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Hydrogen Sulfide (H2S)-based therapy for TIIDM and obesity-associated metabolic deficits: Hydrogen Sulfide (H2S) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 23/July/2017, 11.52 pm

Hydrogen Sulfide (H2S)-based therapy for TIIDM and obesity-associated metabolic deficits: Hydrogen Sulfide (H2S) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 23/July/2017, 11.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite…

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Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Artesunate, a derivative of artemisinin isolated from Artemesia annal l, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 23/July/2017, 11.41 pm

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Artesunate, a derivative of artemisinin isolated from Artemesia annal l, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 23/July/2017, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Natural product-based therapy for glucose homeostasis and TIIDM: Artesunate, a derivative of artemisinin isolated from Artemesia Annua L, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of  Sox4 and its target gene Amysin,  23/July/2017, 11.33 pm

Natural product-based therapy for glucose homeostasis and TIIDM: Artesunate, a derivative of artemisinin isolated from Artemesia Annua L, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of  Sox4 and its target gene Amysin,  23/July/2017, 11.33 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014 issue of the Journal “Journal of Experimental…

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Life-extension therapy: Prednisolone inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 23/July/2017, 12.30 am

Life-extension therapy: Prednisolone inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 23/July/2017, 12.30 am 960 720 Dr Boomi's Genom-2-Discovery Center

What they say? A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates…

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Natural product-based therapy for Cardiomyopathy: α-Lipoic acid, isolated from Broccoli, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 23/July/2017, 12.08 pm

Natural product-based therapy for Cardiomyopathy: α-Lipoic acid, isolated from Broccoli, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 23/July/2017, 12.08 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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