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Ideas

August 5, 2017

Natural product-derived therapy for anxiety and depression:  Curcumin, isolated from Turmeric, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 5/August/2017, 11.15 pm

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
August 4, 2017

Molecular therapy for CyclinD3-CDK6 overexpressing cancers: Ivermectin inhibits the activity of glycolytic enzymes 6-phosphofructokinase and pyruvate kinase M2, decreases antioxidants NADPH and glutathione levels, increases reactive oxygen species levels, promotes apoptosis, and inhibits the progression of CyclinD3-CDK6 overexpressing cancers via down regulation of its target gene, 8/July/2017, 1.00 am

Introduction: What they say A study from Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; and Department of Genetics, Harvard Medical School, Boston, Massachusetts, […]
August 4, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM:  A therapeutic mix encompassing  Indole-3-Carbinol (13C) and Ankaflavin decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 8/August/2017, 1.00 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
August 4, 2017

Molecular therapy for brain tumor and oesophageal squamous cell carcinoma:  Ivermecitin inhibits the expression of Integrin a7 (ITGA7), impairs laminin-induced/FAK mediated signalling, inhibits the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 8/July/2017, 12.53 am

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; […]
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