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Ideas

August 1, 2017

 Life-extension therapy: Nimbolide, isolated from Neem tree (Azadirachta indica), inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 1/August/2017, 11.55 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
July 31, 2017

Molecular therapy for glioblastoma: Monascin, isolated from Monascus purpureus, inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 1/August/2017, 12.10 pm

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
July 31, 2017

Natural product-derived exercise mementics therapy for Metabolic disease: Rutin, isolated from Saussurea heteromalla  and Fagoyrum Tataricum (buckwheat), increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 31/July/2017, 11.41 pm

Introduction: What they say A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows […]
July 31, 2017

Natural product-derived therapy for heart regeneration and repair: Capsaicin, isolated from Cayenne pepper and among others, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 31/July/2017, 10.31 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
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