Ideas

Yoga therapy for Myocardial Infarction: Yoga therapy inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 1/July/2017, 11.30 pm
Yoga therapy for Myocardial Infarction: Yoga therapy inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 1/July/2017, 11.30 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study, was published in the 7 March  2013 issue of Nature,  by Prof Dimmler, Boon, and others. What we…

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Cardiac rejuvenation therapy: Deoxyactein, isolated from the root and rhizomes of black cohosh (Cimicifuga racemosa), suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 1/July/2017, 10.53 am
Cardiac rejuvenation therapy: Deoxyactein, isolated from the root and rhizomes of black cohosh (Cimicifuga racemosa), suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 1/July/2017, 10.53 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Deoxyactein, isolated  from the root and rhizomes of black cohosh (Cimicifuga racemosa),  suppresses tumor suppressor INK4a/p16…

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Natural product-derived therapy for heart regeneration and repair: Moringin, isolated from Moringa Oleifera, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 1/July/2017, 10.02 pm
Natural product-derived therapy for heart regeneration and repair: Moringin, isolated from Moringa Oleifera, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 1/July/2017, 10.02 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA; and Baylor…

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Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis suppressors TAp63 and TPM, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 1July/2017, 12.48 am
Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis suppressors TAp63 and TPM, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 1July/2017, 12.48 am 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them will die; (ii) cancer…

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Natural product-based therapy for Inflammatory bowel disease (IBD): Shikonin, isolated from Zi Cao, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 7/July/2017, 12.35 am
Natural product-based therapy for Inflammatory bowel disease (IBD): Shikonin, isolated from Zi Cao, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 7/July/2017, 12.35 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK shows that “Oncostatin…

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Molecular Hydrogen therapy for middle aged TIIDM patients: Hydrogen-rich water therapy decreases DNA-PK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down regulation of its target gene, 1/July/2017, 12.11 am
Molecular Hydrogen therapy for middle aged TIIDM patients: Hydrogen-rich water therapy decreases DNA-PK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down regulation of its target gene, 1/July/2017, 12.11 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Laboratory of Obesity and Aging Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA; and Laboratory of…

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