Ideas

January 19, 2018

Published by admin_auro at January 19, 2018

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Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Melatonin, Epicatechin and Matrine (MNEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 19/January/2018, 10.59 pm

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]

January 19, 2018

Published by admin_auro at January 19, 2018

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Molecular therapy for Diabetic nephropathy (DN): A pharmaceutical mixture encompassing Pyridoxamine and Sildenafil (PAS) increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 19/January/2018, 10.51 pm

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may protect against the […]

January 19, 2018

Published by admin_auro at January 19, 2018

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Natural product-derived therapy for blood-stage Plasmodium infection: Fisetin, isolated from A. greggi , A. berlanderi, strawberry among others, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 19/January/2018, 10.41 am

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]

January 18, 2018

Published by admin_auro at January 18, 2018

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Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF) inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/January/2017, 12.27 pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]