Ideas

January 11, 2018

Published by admin_auro at January 11, 2018

Categories

Cancer
Ideas

Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of DNA-repair protein hMSH and the apoptosis-inducing protein FasL, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 11/January/2017, 11.04 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]

January 11, 2018

Published by admin_auro at January 11, 2018

Categories

Combinatorial therapy for reversing TIIDM: A pharmaceutical mixture encompassing (TMZATX) Trimetazidine (TMZ) and Astaxanthin (ATX) augments the expression of FGF19 and FGF1, attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 11/January/2017, 10.51 pm

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]

January 11, 2018

Published by admin_auro at January 11, 2018

Categories

Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: A therapeutic mix encompassing Aspalathin and Nothofagin, isolated from Rooibos, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 11/January/2018, 10.37 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]

January 10, 2018

Published by admin_auro at January 10, 2018

Categories

Anti-infective Therapy: Fluvastatin, a lipid-lowering drug used in the treatment of hypercholesterolemia and cardiovascular disease, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 10/January/2017, 11.11 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]