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Ideas

July 21, 2017

Natural product therapy for glucose homeostasis and TIIDM: Artesunate, isolated from Artemesia Annua L, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 22/July/2017, 12.24 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, […]
July 21, 2017

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Hypaphorine increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 22/July/2017, 12.15 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
July 21, 2017

Antiviral therapy against Neuroinvasive West Nile virus: Metformin, the widely used drug in the treatment of TIIDM, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 22/July/2017, 12.08 am

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
July 20, 2017

Natural product-derived therapy for prostate cancer: Linalool, one of the components of Coriander seeds, lavender and among others, inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 21/July/2017, 1.14 am

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]
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