Ideas

January 9, 2018

Published by admin_auro at January 9, 2018

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Vitamin-based Combinatorial therapy for reversing TIIDM: A pharmaceutical mixture encompassing Pyridoxamine and Vitamin K1 (PMVK1)augments the expression of FGF19 and FGF1, attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 9/January/2017, 11.39 pm

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]

January 8, 2018

Published by admin_auro at January 8, 2018

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Molecular therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing α-lipoic acid, Epicatechin and Marine (LAEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 8/January/2018, 10.56 pm

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]

January 8, 2018

Published by admin_auro at January 8, 2018

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Cancer
Ideas

Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor/metastasis suppressors CCM3/KRIT1 and TIMP3, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 8/January/2017, 10.48 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]

January 8, 2018

Published by admin_auro at January 8, 2018

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Lifespan extension therapy: Tomatidine, isolated from unripe tomato, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 8/January/2017, 10.41 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]