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December 10, 2017
Published by admin_auro at December 10, 2017
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Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Carvedilol[Trade name: Coreg], Nonselective beta/alpha1 blocker used in the treatment of myocardial dysfunction and hypertension, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/December/2017, 9.59 am

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
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December 10, 2017
Published by admin_auro at December 10, 2017
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Activation of the PD-1 pathway for Pain therapy: Punicalagin, isolated from Pomegranate,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 10/December/2017, 7.13 am

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
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December 10, 2017
Published by admin_auro at December 10, 2017
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Amino acid-based therapy for Non-alcoholic fatty liver disease (NAFLD): D-Serine promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD) via down regulation of its target gene, 10/December/2017, 6.07 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while only 6-25% of Asian populations suffer from it; […]
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December 10, 2017
Published by admin_auro at December 10, 2017
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Lifespan extension therapy:  Naringenin, isolated from from Grapefruits, increases life span via up-regulation of its target gene BubR1, 10/December/2017, 6.21 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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