Ideas

August 13, 2017

Molecular therapy for glioblastoma: Magnolol, isolated from bark of the Houpu magnolia, inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 13/August/2017, 11.27 pm

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
August 13, 2017

Natural product-derived Ptpn2 pathway blockade enhances the efficacy of Cancer immunotherapy: Myrtenal , isolated from Mint, inhibits the expression of protein tyrosine phosphatase PTPN2, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 13/August/2017, 11.14 pm

Introduction:What they say: A recent study from Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA; Broad Institute of Harvard and Massachusetts Institute of […]
August 13, 2017

Molecular therapy for brain tumor and oesophageal squamous cell carcinoma:  Ivermectin inhibits the expression of Integrin a7 (ITGA7), impairs laminin-induced/FAK mediated signalling, inhibits the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 13/August/2017, 10.17 pm

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; […]
August 13, 2017

Natural product-derived therapy for Chronic Myeloid leukaemia (CML): Artimesinin, isolated from Artemesia Annua L, decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 13/August/2017, 10.08 pm

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; […]
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