Ideas

Vitamin-based Life-extension therapy: ATRA (A form of Vitamin-A) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 22/May/2017, 11.52 pm
Vitamin-based Life-extension therapy: ATRA (A form of Vitamin-A) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 22/May/2017, 11.52 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Vitamin-based therapy for pulmonary arterial hypertension: Cholecalciferol (a form of Vitamin-D) inhibits the development of pulmonary arterial hypertension via down regulation of Notch3 and its target gene Hes-5, 22/May/2017, 9.53 am
Vitamin-based therapy for pulmonary arterial hypertension: Cholecalciferol (a form of Vitamin-D) inhibits the development of pulmonary arterial hypertension via down regulation of Notch3 and its target gene Hes-5, 22/May/2017, 9.53 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in General…

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Anti-telomerase cancer therapy: Metformin, the widely used drug in the treatment of TIIDM, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/May/2017, 9.23 am
Anti-telomerase cancer therapy: Metformin, the widely used drug in the treatment of TIIDM, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/May/2017, 9.23 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1…

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Natural product-derived therapy for Metastatic cancers: Myrtenal, found in Cardamom, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 22/May/2017, 8.51 am
Natural product-derived therapy for Metastatic cancers: Myrtenal, found in Cardamom, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 22/May/2017, 8.51 am 150 150 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Music-based regenerative therapy for improving memory in aged individuals: Music therapy increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 22/May/2017, 8.45 am
Music-based regenerative therapy for improving memory in aged individuals: Music therapy increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 22/May/2017, 8.45 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA;  Paul F. Glenn Center for the Biology of Aging,…

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Natural product-derived antiviral therapy for HIV virus: Cepharanthine, isolated from Stephania cephalantha Hayata, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 22/May/2017, 6.18 am
Natural product-derived antiviral therapy for HIV virus: Cepharanthine, isolated from Stephania cephalantha Hayata, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 22/May/2017, 6.18 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, New York, USA shows…

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