Ideas

December 15, 2017

Published by admin_auro at December 15, 2017

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Cancer
Ideas

Natural product-derived therapy for enhancing anti-cancer immunity: Andrographolide, isolated from Andrographis paniculata, decreases the level of LATS1/2 (large tumor suppressor 1 and 2), increases immunogenicity of tumors, enhances anti-tumor immune responses, and inhibits tumor growth via down regulation of its target gene, 16/December/2017, 12.29 am

Introduction: What they say: A study from the Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA shows that […]

December 15, 2017

Published by admin_auro at December 15, 2017

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Molecular therapy for inflammation and arthritis: R-flurbiprofen increases IL-9 levels, increases proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via upregulation of its target genes, 15/December/2017, 11.36 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]

December 15, 2017

Published by admin_auro at December 15, 2017

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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy in Glioblastoma: A therapeutic mix encompassing Gedunine, Dianhydrogalactitol, EGCG, Salinomycin, Simvastatin and Fluoxetine (GDESSF) inhibits oncoproteins EGFR, and Bcl-xl expression, increases tumor suppressor p53 expression, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 15/December/2017, 11.23 pm

Introduction:What they say: A recent study from Department of Molecular and Medical Pharmacology, David Geffen UCLA School of Medicine, Los Angeles, California, USA; Jonsson Comprehensive Cancer […]

December 15, 2017

Published by admin_auro at December 15, 2017

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Lifespan extension therapy: Pyrroloquinoline quinone (PQQ), isolated from Kiwifruits, increases life span via up-regulation of its target gene BubR1, 15/December/2017, 10.05 am

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]