Ideas

December 12, 2017

Published by admin_auro at December 12, 2017

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Vitamin-based therapy for Diabetic retinopathy: Pyridoxamine (PM), a form of Vitamin B6, inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 13/December/2017, 1.07 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]

December 12, 2017

Published by admin_auro at December 12, 2017

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Molecular therapy for Cardiomyopathy: A pharmacological mixture encompassing Trimetazidine (TMZ) and Astaxanthin (ATX) [TMZATX] decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 13/December/2017, 1.00 am

Introduction: What they say A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]

December 12, 2017

Published by admin_auro at December 12, 2017

Categories

Ideas
Pain

Activation of the PD-1 pathway for Pain therapy: Trimetazidine (TMZ), used in the treatment of Angina Pectoris, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 13/December/2017, 12.23 am

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]

December 12, 2017

Published by admin_auro at December 12, 2017

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Natural product-derived therapy for improving cardiac contractility and attenuating pathogenesis associated with Myocardial infarction: A pharmaceutical mixture encompassing Sulforaphane, Oleanolic acid, and Naringenin decreases GRK2 (G Protein-Coupled Receptor Kinase 2) and GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, increases cardiac contractility, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, promotes heart healing and inhibits glucose intolerance, via up regulation of its target gene, 13/December/2017, 12.12 pm

Introduction: What they say: A recent study, from Department of Medicine, Division of Cardiology, Dept of Cell Biology, and Department of Molecular Genetics, Duke University Medical […]