Ideas

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Licochalcone A (Lico A), isolated from Glycyrrhiza glabra (Liquorice), and Glycyrrhiza inflata, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 9/May/2017, 8.47 am
Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Licochalcone A (Lico A), isolated from Glycyrrhiza glabra (Liquorice), and Glycyrrhiza inflata, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 9/May/2017, 8.47 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates…

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Natural product-derived therapy for Allergic rhinitis: Ampelopsin [AMP; also called dihydromyricetin (DHM)], a flavonoid mainly found in Ampelopsis grossedentata (commonly known as Mayeam) inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 7/May/2017, 11.46 pm
Natural product-derived therapy for Allergic rhinitis: Ampelopsin [AMP; also called dihydromyricetin (DHM)], a flavonoid mainly found in Ampelopsis grossedentata (commonly known as Mayeam) inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 7/May/2017, 11.46 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: Ampelopsin [AMP; also called dihydromyricetin (DHM)], a flavonoid mainly found in Ampelopsis grossedentata…

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Natural product-derived therapy for Metastatic cancers: Solasodine, found in Solanum melongena, increases the expression of metastasis suppressor BTG2 (B cell translocation gene 2 ) and the tumor suppressor INK4a , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 7/May/2017, 11.24 pm
Natural product-derived therapy for Metastatic cancers: Solasodine, found in Solanum melongena, increases the expression of metastasis suppressor BTG2 (B cell translocation gene 2 ) and the tumor suppressor INK4a , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 7/May/2017, 11.24 pm 150 150 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Amino acid-derived regenerative therapy for improving memory in aged individuals: Taurine (2-aminoethanesulfonic acid), found in Cottage cheese and Granola among others, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 7/May/2017, 6.43 am
Amino acid-derived regenerative therapy for improving memory in aged individuals: Taurine (2-aminoethanesulfonic acid), found in Cottage cheese and Granola among others, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 7/May/2017, 6.43 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center for the Biology of…

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Natural product-derived therapy therapy for Stroke: Paeoniflorin, isolated from Paeonia lactiflora pall and Paeoniae radix among others, attenuates hippocampal neurons injury and ameliorates stroke damage and neurological deficits via up regulation of its target gene BDNF, 7/May/2017, 6.13 am
Natural product-derived therapy therapy for Stroke: Paeoniflorin, isolated from Paeonia lactiflora pall and Paeoniae radix among others, attenuates hippocampal neurons injury and ameliorates stroke damage and neurological deficits via up regulation of its target gene BDNF, 7/May/2017, 6.13 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Paeoniflorin (PF), isolated from Paeonia Lactiflora, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 7/May/2017, 5.51 am
Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Paeoniflorin (PF), isolated from Paeonia Lactiflora, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 7/May/2017, 5.51 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates…

read more
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