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Ideas

June 20, 2017

Natural product-derived therapy for heart regeneration and repair: Icariin, isolated from Epimedium/Horny Goat weed, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 20/June/2017, 11.00 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
June 20, 2017

Natural product-derived therapy for brain tumor and oesophageal squamous cell carcinoma: Cirsilol, a flavone isolated from Achillea fragrantissima, inhibits the expression of Integrin a7 (ITGA7), impairs laminin-induced/FAK mediated signalling, inhibits the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 20/June/2017, 10.46 pm

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; […]
June 20, 2017

The PD-1 pathway activation for Pain therapy: Pyruvate, the end product of glycolysis, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 20/June/2017, 10.51 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
June 20, 2017

Low-intensity Electroporal shock wave-based regenerative therapy for muscular atrophy: Low-intensity Electroporal shock wave therapy increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 20/June/2017, 10.35 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]
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