Ideas

December 1, 2017

Molecular therapy for Stroke: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Perpheral vascular disease, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 1/December/2017, 6.44 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
December 1, 2017

Antiviral therapy for HIV virus:  A pharmaceutical mixture encompassing  Cidofovir and Ribavirin (CR) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 1/December/2017, 5.22 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Antiviral therapy for HIV virus:  A pharmaceutical mixture encompassing  Cidofovir and Ribavirin (CR) increases Heme […]
November 30, 2017

Activation of the PD-1 pathway for Pain therapy: Glycine, a non-essential amino acid and neurotransmitter, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 1/December/2017, 12.36 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
November 30, 2017

Molecular therapy for muscle atrophy and wasting: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 1/December/2017, 12.03 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
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