Ideas

September 13, 2017

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Ursodeoxycholic acid (UDCA) [Trade name: Actigall, Udcasid] promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 12/September/2017, 9.49 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while only 6-25% of Asian populations suffer from it; […]
September 13, 2017

Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis/tumor suppressors  Big-H3 and TIPE2, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 13/September/2017, 9.44 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
September 12, 2017

Natural product-based therapy for TIIDM: A pharmaceutical mixture encompassing Celastrol, Mangiferin, Fisetin, Spermidine, and Ursolic acid (CMFSU) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 13/September/2017, 12.13 am

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
September 12, 2017

Natural product-based therapy for anxiety and depression: Naringenin, isolated from Citrus fruits, increases PHF8 levels, augments  the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 12/September/2017, 12.07 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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