Ideas

August 16, 2017

Natural product-derived therapy for inflammation and arthritis: Kaempferol, isolated from Greater cappers, Kale and among others, increases IL-9 levels, increases proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 16/August/2017, 11.23 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
August 15, 2017

 Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Salvianolic acid B, Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D dissolved in Hydrogen-rich water activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 15/August/2017, 11.59 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 15, 2017

Small molecule-based exercise mementics therapy for Metabolic disease: 5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 15/August/2017, 11.55 pm

Introduction: What they say  A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows […]
August 15, 2017

Natural product-derived therapy for tuberculosis: Geniposide, isolated from Gardenia,  deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 15/August/2017, 11.49 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
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