Ideas

November 24, 2017

Published by admin_auro at November 24, 2017

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Ideas
Pain

Activation of the PD-1 pathway for Pain therapy: D-Serine increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 24/November/2017, 1.21 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]

November 24, 2017

Published by admin_auro at November 24, 2017

Categories

Ideas
Stroke

Natural product-derived therapy for Stroke: Safranal, isolated from Saffron, Rooibos and among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 24/November/2017, 8.14 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]

November 23, 2017

Published by admin_auro at November 23, 2017

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Cancer
Ideas

Combinatorial therapy for prostate cancer: A therapeutic mix encompassing Calcitriol, Mitoxantrone, Despiramine, 17-DMAG, Salinomycin, Lovastatin, and Jasmonate (CMDDSLJ) inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 23/November/2017, 12.15 pm

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]

November 23, 2017

Published by admin_auro at November 23, 2017

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Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Safrnal, Catalpol, Cholecalciferol, Maresin, Ursolic acid, DIM, Isoliquiritigenin, & Lutein (SCCMUDIL) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 23/Novem ber/2017, 7.40 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]