Ideas

November 19, 2017

Published by admin_auro at November 19, 2017

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Cancer
Ideas

Natural product-based combination therapy targeting cancer stem cells in Myeloid leukaemia (ML): A therapeutic mix encompassing Artemisinin, Glimepiride, Fenofibrate and Calcitriol inhibits cytosolic aminotransferase BCAT1 expression, increases a-ketoglutarate levels, promotes degradation of HIF1a levels, increases DNA demethylase levels, promotes hypomethylation, increases the expression of tumor suppressor genes, inhibits leukaemia-initiating potential of AML cells, promotes differentiation of AML cells, and inhibits cancer progression in AML via up-regulation of its target gene, 19/November/2017, 11.41 pm

Introduction to what they say: A study from the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany; Division of Stem […]

November 18, 2017

Published by admin_auro at November 18, 2017

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Molecular therapy for Glaucoma: Rosiglitaone, an insulin sensitizer, increases Nmnat1 expression, increases NAD+ levels, improves neuroanl dysfunction, and protects against glaucoma via down regulation of its target gene, 18/October/2017, 11.25 pm

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]

November 18, 2017

Published by admin_auro at November 18, 2017

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Lifespan extension therapy:Tesaglitazar (AZ242), an insulin sensitizer, may increase life span via up-regulation of its target gene BubR1, 19/October/2017, 11.14 pm

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]

November 18, 2017

Published by admin_auro at November 18, 2017

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Natural product-derived therapy for attenuating associated with Myocardial infarction: Formononetin, found in Trifolium pratense and Maackia amurensis, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 18/November/2017, 8.19 am

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems […]