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Ideas

June 6, 2017

Natural product therapy for KRAS/LKB1-mutant lung cancer: Cirsilol, isolated from Achillea Fragrantissima, increases the levels of tumor suppressor proteins, inhibits the expression of urea cycle enzyme carbamoyl phosphate synthetase-1 (CSP1), decreases pyrimidine pools, stalls DNA synthesis, and inhibits the progression of KRAS/LKB1-mutated lung cancers via up regulation of its target gene, 6/June/2017, 11. 15pm

Introduction: What they say A study from the Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas 75390, USA; Department of Pediatrics, UT Southwestern […]
June 6, 2017

Natural product-derived therapy for metastasis: Berberine, one of the components of Berberis, Phellodendron amurense, and Guduchi among others, inhibits the expression of IL-6/8, decreases the experssion of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 6/June/2017, 11.14 pm

Introduction: What they say: A study from Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA; Johns Hopkins Physical Sciences-Oncology Center, […]
June 5, 2017

Natural product-derived therapy for Stroke: Salidorside, isolated from Rhodiola Rhosea, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 6/June/2017, 12.38 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
June 5, 2017

Natural product-derived (exercise mementics) therapy for Metabolic disease: Epigallocatechin gallate (EGCG), isolated from Green tea, increases PPARδ levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 6/June/2017, 12.37 am

Introduction: What they say A study from the Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological […]
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