Ideas

Natural product-derived therapy for Myocardial Infarction: Salvianolic acid B, isolated from Salvia Miltiorrhiza Bge, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 29/March/2017, 11.11 am
Natural product-derived therapy for Myocardial Infarction: Salvianolic acid B, isolated from Salvia Miltiorrhiza Bge, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 29/March/2017, 11.11 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-derived Life-extension therapy: Cryptotanshinone (CPT), found in Salvia miltiorrhiza Bunge, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 29/March/2017, 7.54 am
Natural product-derived Life-extension therapy: Cryptotanshinone (CPT), found in Salvia miltiorrhiza Bunge, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 29/March/2017, 7.54 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Salvianolic acid A, one of the main components of Salvia Miltiorrhiza Bge, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 29/March/2017,4.53 am
Natural product-derived PD-1 pathway blockade for Human cancer therapy: Salvianolic acid A, one of the main components of Salvia Miltiorrhiza Bge, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 29/March/2017,4.53 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK shows that “Glycogen Synthase…

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Natural product-derived therapy for prostate cancer bone metastasis: Linalool, found in coriander, sweet orange (Citrus sinensis), tomato, oils of rose, neroli, lavender, laurel and sweet basil (Ocimum basilicum) among others, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 29/March/2017, 4.36 am
Natural product-derived therapy for prostate cancer bone metastasis: Linalool, found in coriander, sweet orange (Citrus sinensis), tomato, oils of rose, neroli, lavender, laurel and sweet basil (Ocimum basilicum) among others, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 29/March/2017, 4.36 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of Shh-IL6-RANKL Signaling Network Promotes…

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Natural product-derived therapy for enhancing the efficacy of tyrosine-kinase inhibitor (TKI) therapy in BCR-ABL-induced Human leukemia: Salvianolic acid A, one of the main components of Salvia Miltiorrhiza Bunge, decreases the expression of oncoproteins c-FOS, DUSP1 and BCR-ABL, inhibits TKI resistance, restores treatment responsiveness, increases therapeutic index of anticancer drugs, and cure CML and kinase-driven cancers via up-regulation of its target gene, 28/March/2017, 2.31 pm
Natural product-derived therapy for enhancing the efficacy of tyrosine-kinase inhibitor (TKI) therapy in BCR-ABL-induced Human leukemia: Salvianolic acid A, one of the main components of Salvia Miltiorrhiza Bunge, decreases the expression of oncoproteins c-FOS, DUSP1 and BCR-ABL, inhibits TKI resistance, restores treatment responsiveness, increases therapeutic index of anticancer drugs, and cure CML and kinase-driven cancers via up-regulation of its target gene, 28/March/2017, 2.31 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Division of Experimental Hematology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA; Division of Pathology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio,…

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Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Salvianolic acid B, isolated from Salvia Miltiorrhiza Bunge, promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 28/March/2017, 10.08 am
Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Salvianolic acid B, isolated from Salvia Miltiorrhiza Bunge, promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 28/March/2017, 10.08 am 150 150 Dr Boomi's Genom-2-Discovery Center

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Salvianolic acid B, isolated from Salvia Miltiorrhiza Bunge, promotes…

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