Ideas

Natural product-based Lifespan extension therapy: Polydatin (PD), isolated from the root and rhizome of herb Polygonum cuspidatum, activates autophagy and extends lifespan via up regulation of ATG5, 19/March/2017, 9.45 am
Natural product-based Lifespan extension therapy: Polydatin (PD), isolated from the root and rhizome of herb Polygonum cuspidatum, activates autophagy and extends lifespan via up regulation of ATG5, 19/March/2017, 9.45 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published in the online…

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Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God Vine, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 19/March/2017, 8.24 pm
Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God Vine, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 19/March/2017, 8.24 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God Vine, increases Heme oxygenase…

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MiRNA-based Life-span extension therapy: MiR-761 may increase lifespan by suppressing mTOR pathway, 19/March/2016, 7.49 am
MiRNA-based Life-span extension therapy: MiR-761 may increase lifespan by suppressing mTOR pathway, 19/March/2016, 7.49 am 150 150 Dr Boomi's Genom-2-Discovery Center

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity promoters.”  From research findings…

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Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Berberine, one of the major components of Berberis, Berberis aristata, Oregon grape, Hydrastis canadensis, and Phellodendron amurense, among others, promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 18/March/2017, 10.04 am
Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Berberine, one of the major components of Berberis, Berberis aristata, Oregon grape, Hydrastis canadensis, and Phellodendron amurense, among others, promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 18/March/2017, 10.04 am 150 150 Dr Boomi's Genom-2-Discovery Center

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Berberine, one of the major components of Berberis, Berberis aristata,…

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Natural product-derived therapy for glucose homeostasis and TIIDM: Scopoletin, isolated from Scopolia Japonica, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of its target gene Sox4, 18/March/2017, 8.54 am
Natural product-derived therapy for glucose homeostasis and TIIDM: Scopoletin, isolated from Scopolia Japonica, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of its target gene Sox4, 18/March/2017, 8.54 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014…

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Natural product-derived therapy for Myocardial Infarction: Calycosin, isolated from Astragalus Membranaceuss, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 18/March/2017, 7.39 pm
Natural product-derived therapy for Myocardial Infarction: Calycosin, isolated from Astragalus Membranaceuss, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 18/March/2017, 7.39 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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