Ideas

July 30, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Capsaicin, isolated from Chilli pepper,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gen, 31/July/2017, 12.17 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
July 30, 2017

Natural product therapy for pulmonary arterial hypertension: Capsaicin, isolated from Chilli pepper, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3,30/July/2017, 11.58 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the […]
July 30, 2017

Cardiac rejuvenation therapy: Artesunate, , a derivative of  Artemisinin isolated  from Artemesia Annua L,  suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 30/July/2017, 11.46 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Cardiac rejuvenation therapy: Artesunate,, a derivative of  Artemisinin isolated  from Artemesia Annua L,  suppresses tumor suppressor […]
July 29, 2017

Natural product-derived antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Artemisinin, isolated from Artemesia annua L, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 29/July/2017, 11.06 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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