Ideas

November 3, 2017

Published by admin_auro at November 3, 2017

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Molecular therapy for attenuating pathogenesis associated with Myocardial infarction: Ciglitazone, an anti-hyperglycemic drug, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 3/November/2017, 7.10 am

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems […]

November 3, 2017

Published by admin_auro at November 3, 2017

Categories

Ideas
NAFLD

Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Astaxanthin, isolated from heaematococcus pluvialis, and Pandalus, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 3/November/2017, 7.03 am

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]

November 1, 2017

Published by admin_auro at November 1, 2017

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Ageing
Ideas

Natural product-based therapy for ageing-associated diseases: A therapeutic mix encompassing Lycopene, Ellagic acid & Schisandrin B (LES), isolated from Tomato, Strawberry, schisandra chinensis, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 2/November/2017, 12.05 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]

November 1, 2017

Published by admin_auro at November 1, 2017

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Natural product therapy for body weight control, energy homeostasis and TIIDM: Emodin, isolated from Rhubarb, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 1/November/2017,11.56 pm

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]