Ideas

October 31, 2017

Published by admin_auro at October 31, 2017

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Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]

October 31, 2017

Published by admin_auro at October 31, 2017

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Antiviral therapy for HIV virus: Ribavirin/Tribavirin, an antiviral medication used in the treatment of RSV infection, hepatitis C, and viral hemorrhagic fever, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 31/October/2017, 10.43am

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]

October 31, 2017

Published by admin_auro at October 31, 2017

Categories

Ageing
Ideas

Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing iallyl disulfide, Isoorientin and Resveratrol (DIR) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 31/September/2017, 10.35 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]

October 31, 2017

Published by admin_auro at October 31, 2017

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Regenerative therapy for muscle atrophy: Simvastatin (Brand name: Zocor), a lipid lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 31/October/2017, 10.25 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]